Amphetamine Class Stimulants

Mechanism of Action:

Amphetamines act by increasing the release of norepinephrine and dopamine and blocking their reuptake.

Amphetamine Class Stimulants:

Dextroamphetamine (generic) – Duration 3-5 hours for immediate release version, duration 4-8 hours for extended release version

Dexedrine (dextroamphetamine) – Discontinued in the U.S.

Procentra (dextroamphetamine) – Duration 3-5 hours

Amphetamine/Dextroamphetamine (generic) – Duration 3-5 hours for immediate release version, duration 4-8 hours for extended release version

Adderall (amphetamine/dextroamphetamine) – Duration 3-5 hours

Adderall XR (amphetamine/dextroamphetamine) – Duration 8-12 hours

Vyvanse (lisdexamfetamine) – a pro-drug that is converted to dextroamphetamine by the liver, duration 9-13 hours

Article written 12/19/09 by Minyang Mao, M.D.

Disclaimer: This article is intended as an educational resource only, and is not intended to be a replacement for treatment. For evaluation and treatment, please contact a qualified mental health professional.

Content © 2009 Minyang Mao, M.D.  All rights reserved.

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